0Oncolytic Virotherapy:
Measles Virus as an agent of tumour destruction
Oncolytic Viruses- Viruses that replicate selectively in tumour tissues and lyse the tumour cells
Virotherapy Benefits (Attenuated Measles virus)
Low risk to patients
§ Selectivity for the tumour
§ Nonpathogenic
§ Non-persistent
§ Genetically stable
Low risk to the population
§ Non-transmissible
§ Pre-Immune population
Several improved strategy
Engineering Measles Virus Tropism
Arming the Virus to Combat Innate Immunity
Noninvasive monitoring
Progressive clinical trials
Measles virotherapy - Safe and highly promising in the treatment of human cancer
